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Capsules containing rice bran oil and fucoxanthin in patients with coronary heart disease

Effects of a supplement containing rice bran oil and fucoxanthin on lipid profile, inflammatory indicators, and clinical and biochemical cardiovascular parameters in patients with coronary artery disease: A randomized clinical trial

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20240717062445N1
Enrollment
50
Registered
2024-07-23
Start date
2025-02-27
Completion date
Unknown
Last updated
2025-02-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Coronary artery disease. Atherosclerotic heart disease of native coronary artery

Interventions

Intervention 1: Intervention group: receiving a standard diet containing olive oil as the main fat source + consuming three capsules of rice bran oil produced by Giltaz company and fucoxanthin produc

Sponsors

Rasht University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
20 Years to 70 Years

Inclusion criteria

Inclusion criteria: Age range 20 to 70 years Not using vitamin and mineral supplements, antioxidants, fiber supplements, omega-3 No history of kidney disease, no current alcohol consumption Coronary artery occlusion diagnosed by angiography by a cardiologist. No current consumption of alcoholic beverages

Exclusion criteria

Exclusion criteria: Changes in the patient's coronary disease treatment plan during the study Changing the type of drugs used, effective factors studied Creating any kind of dissatisfaction in the field of oil taste and...

Design outcomes

Primary

MeasureTime frame
Serum lipid profile levels (triglycerides, total cholesterol, LDL-C and HDL-C). Timepoint: At the beginning of the study and 12 weeks later. Method of measurement: BT2000 device.;Fasting blood sugar. Timepoint: At the beginning of the study and 12 weeks later. Method of measurement: BT2000 device.;Serum insulin. Timepoint: At the beginning of the study and 12 weeks later. Method of measurement: BT2000 device.;Glycosylated hemoglobin. Timepoint: At the beginning of the study and 12 weeks later. Method of measurement: ELISA device.;Erythrocyte sedimentation rate. Timepoint: At the beginning of the study and 12 weeks later. Method of measurement: ELISA device.;Glutathione peroxidase activity. Timepoint: At the beginning of the study and 12 weeks later. Method of measurement: ELISA device.;Glutathione reductase activity. Timepoint: At the beginning of the study and 12 weeks later. Method of measurement: ELISA device.;Vitamin E. Timepoint: At the beginning of the study and 12 weeks later. Method of measurement: ELISA device.;HS - C-reactive protein. Timepoint: At the beginning of the study and 12 weeks later. Method of measurement: ELISA device.

Secondary

MeasureTime frame
Mean systolic and diastolic blood pressure. Timepoint: At the beginning of the study and 12 weeks later. Method of measurement: Pressure indicator.;Body mass index. Timepoint: At the beginning of the study and 12 weeks later. Method of measurement: Centimeter and scales.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMarjan Mahdavi Roshan

Rasht University of Medical Sciences

marjanmahdavi60@gmail.com+98 13 3348 6407

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026