Effect of concurrent of curcumin and caffeine on non-alcoholic fatty liver disease

Evaluation the Effect of concurrent of curcumin and caffeine on biochemical markers,oxidative stress, and inflammatory cytokines in individuals with non-alcoholic fatty liver disease (Random Clinical trial Study)

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20240715062438N1

Enrollment

Registered

2024-07-30

Start date

2024-07-22

Completion date

Unknown

Last updated

2024-08-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Non-alcoholic fatty liver disease. Fatty (change of) liver, not elsewhere classified

Interventions

Intervention 1: Intervention group: Eligible participants who met the inclusion criteria were randomly assigned to receive curcumin (Sina curcumin tablets, 40 mg nanomicelles) plus a 200 mg caffeine t

Eligibility

Sex/Gender

All

Age

18 Years to 60 Years

Inclusion criteria

Inclusion criteria: Willingness to participate in the study people aged 18 to 60 years no history of alcohol consumption no other liver disorders, malignancies, cardiovascular, respiratory and kidney disorders no history of weight loss or bariatric surgery in recent years no drug use In the last 3 months the absence of endocrine and metabolic disorders

Exclusion criteria

Exclusion criteria: Pregnancy or breastfeeding in women The patient's unwillingness to continue participating in the study Non-compliance with the supplement Participating in a concurrent trial Allergy to supplements

Design outcomes

Primary

Measure	Time frame
Biochemical markers. Timepoint: 8 weeks. Method of measurement: Colorimetric method.;Oxidative stress. Timepoint: 8 weeks. Method of measurement: Colorimetric method.;Inflammatory cytokine. Timepoint: 8 weeks. Method of measurement: ELISA.	—

Secondary

Measure	Time frame
Creatinine level. Timepoint: 8 weeks. Method of measurement: colorimetric.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMajid Bagheri

Yasouj University of Medical Sciences

behnaalipoor@gmail.com0743337251

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026