Diseases of the respiratory system. Diseases of the respiratory system(J00-J99)
Conditions
Interventions
Intervention 1: Intervention group: (Dexmedetomidine 1 microgram/kg will be infused over 30 minutes and then a maintenance dose of 0.3 microgram/kg/hour for 24 hours/day). Intervention 2: Control grou
Sponsors
Gorgan University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: Patients requiring mechanical ventilation. Patients over 18 years old, Not having COPD
Exclusion criteria
Exclusion criteria: Death of the patient before 24 hours of admission to the ICU Loss criteria to follow up death of the patient The occurrence of drug sensitivity Patients less than 18 years old and more than 80 years old
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Restlessness. Timepoint: Immediately after the end of the infusion and 1, 6, 12, 24 hours after the intervention. Method of measurement: The Richmond questionnaire.;Sedation of patients. Timepoint: Immediately after the end of the infusion and 1, 6, 12, 24 hours after the intervention. Method of measurement: The Ramsay questionnaire. | — |
Secondary
| Measure | Time frame |
|---|---|
| Determining and comparing the average of hemodynamic variables between the two groups. Timepoint: Immediately after the end of the infusion and 1, 6, 12, 24 hours after the intervention. Method of measurement: Pulse oximeter. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMansoor Dailami
Gorgan University of Medical Sciences
Outcome results
None listed