Effect of Topical Desmopressin, Phenylephrine and Tranexamic Acid on the Amount of Bleeding and the Surgeon's Visual Field During Rhinoplasty Surgery

A Comparative Study of the Effect of Topical Desmopressin, Phenylephrine and Tranexamic Acid on the Amount of Bleeding and the Field of Vision of the Surgeon During Rhinoplasty Surgery: A Three-blind Clinical Trial Study

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20240712062409N1

Enrollment

Registered

2024-07-21

Start date

2024-07-31

Completion date

Unknown

Last updated

2024-07-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Condition 1: Rhinoplasty. Condition 2: Deviation of the septum. Deviated nasal septum

Interventions

Intervention 1: The First Intervention Group: The First Intervention Group: Desmopressin Spray, each 100 Ml of DESMEX Nasal Solution Contains 10 Mg of Desmopressin Acetate as an Active Ingredient and

Eligibility

Sex/Gender

All

Age

18 Years to 55 Years

Inclusion criteria

Inclusion criteria: Age 18 to 55 Patient Satisfaction Normal Hemoglobin Normal Prothrombin Time Normal Partial Thromboplastin Time Normal Platelets Normal Hematocrit

Exclusion criteria

Exclusion criteria: Alcohol Consumption in the Last Week Smoking and Addiction Aspirin and Vitamin E Consumption in the Last Week Cardiovascular Diseases Coagulation Problems High Blood Pressure Diabetes Brain Diseases Morbid Obesity Severe Hypotension During Surgery Patients Who Require Severe Osteotomy from the Surgeon's Point of View Surgery Time more than 2 Hours

Design outcomes

Primary

Measure	Time frame
Bleeding Rate. Timepoint: 15, 30, 45 and 90 Minutes After Using the Drug During Surgery. Method of measurement: Blood Gas Weight and Suction Bottle Measurement.;Field of Vision of the Surgeon. Timepoint: 15, 30, 45 and 90 Minutes After Using the Drug During Surgery. Method of measurement: Boezaart Scale.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMohammad Reza Zamani

Hamedan University of Medical Sciences

LVLRE1378@GMAIL.COM+98 81 3821 2979

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026