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A human clinical trial of an Allium jesdianum formulation on kidney stones

An effective herbal formulation of the Allium jesdianum based on Iranian traditional medicine along with its human clinical trial on improving the kidney function in patients suffering from oxalate, or uric kidney stones.

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20240712062398N1
Enrollment
100
Registered
2024-07-20
Start date
2024-12-21
Completion date
Unknown
Last updated
2024-07-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Oxalate urinary stones. Calculus of kidney

Interventions

Intervention 1: Intervention group: patients with oxalate kidney stones. Intervention 2: Intervention group: Patients with uric kidney stones. Intervention 3: Control group: patients with oxalate kidn

Sponsors

Esfahan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Symptomatic or asymptomatic urinary tract stones Stone size equal to 10 mm or less Absence of malignancy with bone metastasis Not suffering from hyperthyroidism, hyperparathyroidism, psychosis or kidney dysfunction (creatinine above 1.4 mg/dL) Not having a structural disorder of the urinary tract or a urinary tract infection No gout or hyperuricemia Not using other traditional products and complementary medicine used in the treatment of urinary stones from one week before the intervention Absence of pregnancy and breastfeeding

Exclusion criteria

Exclusion criteria: Non-compliance with medication orders for more than 1 week Allergy to any component of the herbal product The need for hospitalization due to the severity of symptoms during the study The need for surgery and lithotripsy during the study Urinary tract infection during the study

Design outcomes

Primary

MeasureTime frame
The percentage of stone size change. Timepoint: Before and after the intervention. Method of measurement: with ultrasound based on millimeter units.;Concentration of calcium, sodium, citrate, oxalate, urea, creatinine, uric acid and cystine, phosphorus in urine. Timepoint: Before and after the intervention. Method of measurement: mg/dl.;Number of people with stone removal. Timepoint: Before and after the intervention. Method of measurement: number.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactRasool soltani

Esfahan University of Medical Sciences

soltani@pharm.mui.ac.ir+98 31 3792 0001

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026