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Comparing the sedation effect of intravenous etomidate-fentanyl-midazolam combination with intravenous propofol-fentanyl-midazolam for patients undergoing cataract surgery.

A comparative study of sedation of intravenous etomidate-fentanyl-midazolam combination with intravenous propofol-fentanyl-midazolam for patients undergoing cataract surgery.

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20240710062387N1
Enrollment
120
Registered
2024-09-09
Start date
2024-08-22
Completion date
Unknown
Last updated
2024-09-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cataract. Age-related cataract

Interventions

Intervention 1: Intervention group1: propofol-fentanyl-midazolam (PFM). Intervention 2: Intervention group2: etomidate-fentanyl-midazolam (EFM).

Sponsors

Esfahan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: Candidates for cataract surgery by emulsification method, having (ASA) between 1 and 3, age between 18 and 70 years and having consent to participate in the study

Exclusion criteria

Exclusion criteria: Having Parkinson's disease, claustrophobia (due to the fear of being stuck in a tight place and having no way out, the patient does not allow the surgery to remain on his face and must receive a higher dose of drugs) Weight more than one hundred kilograms ( Because drug bioavailability in patients with high BMI is different from patients with normal BMI and the dosage of drugs may need to be changed, which interferes with the study), Shortness of breath, psychosis, Alzheimer Occurrence of acute cardiac ischemia in three In the last month, Having a history of drug Abuse, Having a history of allergy to anesthetics, Pregnancy, Having a blood pressure base of more than 180/110

Design outcomes

Primary

MeasureTime frame
Sedation score and surgeon and patient satisfaction. Timepoint: The degree of sedation at the time of receiving drugs and 5, 10, 20 minutes after the start of surgery in two groups. Method of measurement: RSS sedation rating.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMitra Jabal Ameli

Esfahan University of Medical Sciences

jabalameli@med.mui.ac.ir+98 31 3629 6073

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026