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Comparing the effects of duloxetine and gabapentin drugs on paresthesia after spine surgery

Comparing the effects of duloxetine and gabapentin drugs on paresthesia after spine surgery

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20240706062339N1
Enrollment
90
Registered
2024-12-06
Start date
2024-09-22
Completion date
Unknown
Last updated
2025-01-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

LUMBAR DISK PATIENTS.

Interventions

Intervention 1: Intervention group: Duloxetine at a dose of 30 mg twice a day for one months, which will be received orally capsule. Intervention 2: Intervention group: gabapentin at a dose of 300 mg

Sponsors

Vice President for Research and Technology, Army University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: All patients candidates for spine surgery age between 18 to 60 Have paresthesia after surgery

Exclusion criteria

Exclusion criteria: Known allergy to the drug being tested Abnormal liver and kidney function test Uncontrolled narrow-angle glaucoma Chronic opioid abuser (more than 3 months) Taking tricyclic antidepressants or fluvoxamine pregnant women Patients with psychiatric disorders or seizure disorders

Design outcomes

Primary

MeasureTime frame
PARESTHESIA. Timepoint: At the beginning of the study, one week later, one month later, three months later. Method of measurement: Monofilament test, VAS questionnaire.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAMIRHOSSEINBEHESHTDOOST

Artesh University of Medical Sciences

AMIRHOSSEINBEHESHTDOOST1998@GMAIL.COM+98 901 660 6776

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026