Investigating the effectiveness of injection of lidocaine and articaine anesthesia on heart rate, blood oxygen saturation percentage and blood pressure

Comparison of anesthetic injection lidocaine with articaine on changes in heart rate ,blood oxygen saturation percentage and blood pressure in Candidate patients for tooth extraction: a Randomized clinical trial

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

IRCT

Registry ID

IRCT20240703062318N1

Enrollment

Registered

2024-08-22

Start date

2024-09-22

Completion date

Unknown

Last updated

2024-08-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Condition 1: Blood pressure. Condition 2: heartbeat. Condition 3: Blood oxygen saturation percentage.

Interventions

Intervention 1: Intervention group: Patients receiving persocaine-E which contains lidocaine 2% with epinephrine 1/80000 from Darupakhsh company. Each patient will be injected only once and a carpool

Eligibility

Sex/Gender

All

Age

30 Years to 50 Years

Inclusion criteria

Inclusion criteria: Healthy people between 30 and 50 years old Candidates for extraction of lower jaw teeth

Exclusion criteria

Exclusion criteria: People with cardiovascular, renal, respiratory disease, liver failure and hyperthyroidism pregnant women All diabetic patients People with dental anxiety outside the normal range People who take medications that affect heart rate

Design outcomes

Primary

Measure	Time frame
Number of heartbeats. Timepoint: Before and after injection of anesthesia. Method of measurement: by pulse-oximetry.;Blood oxygen saturation. Timepoint: Before and after injection of anesthesia. Method of measurement: by pulse-oximetry.;Blood pressure. Timepoint: Before and after injection of anesthesia. Method of measurement: Digital pressure gauge device.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSeyed Alireza Fazeli

Gorgan University of Medical Sciences

alirezafazelli15@gmail.com+98 17 3224 1889

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026