Investigating the preventive effect of a drug intervention on an important and vital complication in premature babies (retinopathy of prematurity). Retinopathy of prematurity
Conditions
Interventions
Intervention 1: Intervention group: melatonin oral medication with a dose of 3 mg per kg, which will be started during the first 72 hours of life, orally once a day, at 11:00 PM for 10 consecutive day
Sponsors
Tehran University of Medical Sciences
Eligibility
Sex/Gender
All
Age
No minimum to 3 Days
Inclusion criteria
Inclusion criteria: Obtaining informed consent from parents to enter the study Gestational age less than 34 weeks or weight less than two kilograms Ability to take oral medication Absence of metabolic or genetic disease Absence of kidney and liver diseases
Exclusion criteria
Exclusion criteria: Lack of informed parental consent in entering the study Gestational age more than 34 weeks Digestive obstructions Failure to take medication regularly
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Retinopathy of prematurity. Timepoint: Fourth to sixth week of life. Method of measurement: Ophthalmological examination. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactZiba Mossayebi
Tehran University of Medical Sciences
Outcome results
None listed