spinal cord injury. Injury, poisoning and certain other consequences of external causes
Conditions
Interventions
Intervention 1: Intervention group: In the intervention group, patients with spinal cord injury received fingolimod (Aburihan Pharmaceutical Company)in addition to methylprednisolone (MPSS-Exir Aburih
Sponsors
Mashhad University of Medical Sciences
Eligibility
Sex/Gender
All
Age
20 Years to 60 Years
Inclusion criteria
Inclusion criteria: stable hemodynamic status age between 20 and 60 Patients with acute traumatic spinal cord injury who referred within the first 8 hours
Exclusion criteria
Exclusion criteria: acute non traumatic spinal cord injury Acute spinal cord injury that has been more than 8 hours since the trauma Spinal cord injuries caused by firearms or cold weapons
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Sensorimotor status of patients. Timepoint: Sensory and motor condition of patients are evaluated based on clinical examination immediately after administration (Before the intervention begins) and then at intervals of one month, three months, six months and one year after the intervention. Method of measurement: the sensory-motor condition of patients are evaluated based on American Spinal Injury Association Impairment Scale (AISA).;Sphincter function. Timepoint: administration and evaluation at intervals of six months and one year. Method of measurement: clinical examination and questionnaire. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactShahin Nazarpour
Mashhad University of Medical Sciences
Outcome results
None listed