head and neck squamous cell carcinoma. Squamous cell carcinoma of skin of other and unspecified parts of face
Conditions
Interventions
Intervention 1: Control group: The nutritional advice of the patient was at the level of nutritional recommendations to reduce nutritional complications related to radiotherapy. Intervention 2: Interv
Sponsors
Tehran University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Patients who have been diagnosed with head and neck SCC cancer in T2-T4 stage along with lymph node involvement and are undergoing adjuvant or radical radiotherapy based on the radio-oncologist's diagnosis. Adult patients over 18 years old Patients on oral nutrition.
Exclusion criteria
Exclusion criteria: People who receive enteral or parenteral nutrition before or during the study Patients with uncontrolled acute underlying diseases such as kidney failure and liver failure (high serum levels of urea and creatinine and decrease in GFR, increase in liver enzymes ALT, AST, ALP) receiving any other supportive treatment Patients who die during radiotherapy Patients who do not continue the study for any reason.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Weight. Timepoint: Before the intervention and every two weeks until the end of the intervention. Method of measurement: scales.;Body mass index. Timepoint: Before the intervention and every two weeks until the end of the intervention. Method of measurement: formula.;Mid arm circumference. Timepoint: Before the intervention and every two weeks until the end of the intervention. Method of measurement: tape measure.;Calf circumferences. Timepoint: Before the intervention and every two weeks until the end of the intervention. Method of measurement: tape measure.;EORTC QLQ-C?? score. Timepoint: The beginning and end of the intervention. Method of measurement: questionnaire.;PG-SGA score. Timepoint: The beginning and end of the intervention. Method of measurement: questionnaire. | — |
Secondary
| Measure | Time frame |
|---|---|
| Complete blood count (CBC) measurement. Timepoint: Before and at the end of the intervention. Method of measurement: patient file.;Serum albumin. Timepoint: Before and at the end of the intervention. Method of measurement: Autoanalyzer device (spectrophotometry method).;Total protein. Timepoint: Before and at the end of the intervention. Method of measurement: Autoanalyzer device (spectrophotometry method).;The level of electrolytes. Timepoint: Before and at the end of the intervention. Method of measurement: spectrophotometry.;Local recurrence rate. Timepoint: at the end of the intervention. Method of measurement: Radiography.;Two-year disease-free survival. Timepoint: Two years after the intervention. Method of measurement: patient file.;Treatment tolerance (finishing the course of radiotherapy without interruption due to physical weakness). Timepoint: at the end of the intervention. Method of measurement: patient file. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMahsa Malekahmadi
Tehran University of Medical Sciences
Outcome results
None listed