propolis supplementation for the eradication of Helicobacter pylori

Investigating the effectiveness of propolis as an adjuvant treatment for the eradication of Helicobacter pylori: Double-blind randomized controlled clinical trial

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20240622062210N1

Enrollment

Registered

2024-08-01

Start date

2024-07-22

Completion date

Unknown

Last updated

2024-08-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients with Helicobacter pylori infection. Other diseases of stomach and duodenum

Interventions

Intervention 1: Intervention group: Propolis/ Propolis group will receive 300 mg propolis capsules (containing 50 mg propolis extract) 2 times a day for 14 days. Intervention 2: Control group: placebo

Eligibility

Sex/Gender

All

Age

18 Years to 60 Years

Inclusion criteria

Inclusion criteria: Patients aged 18-60 years old Helicobacter pylori infected patients

Exclusion criteria

Exclusion criteria: Chronic diseases such as diabetes, CKD, Malignancy, gallbladder disorders, peptic ulcer and upper gastrointestinal surgery Consumption of propolis or other antioxidant supplements or herbal drugs over the past 3 months allergy to propolis

Design outcomes

Primary

Measure	Time frame
Fecal anti-Helicobacter pylori antigen. Timepoint: 14 days. Method of measurement: Measuring fecal anti-Helicobacter pylori antigen using PCR method.;Helicobacter pylori caused gastrointestinal complaints. Timepoint: 14 days. Method of measurement: Helicobacter pylori caused gastrointestinal complaints questionnaire scale.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMohammadreza Pashaei

Oroumia University of Medical Sciences

dr.pashaei@yahoo.com+98 44 3234 3477

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026