Ziziphus Jujuba extract syrup in hypertension

The effect of Ziziphus Jujuba syrup on the lipid profile and oxidative stress in hyperlipidemic- hypertensive patients

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20240622062206N2

Enrollment

Registered

2025-06-01

Start date

2025-04-04

Completion date

Unknown

Last updated

2025-07-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Condition 1: Hypertension. Condition 2: Hyperlipidemia. Essential (primary) hypertension Hyperlipidemia, unspecified

Interventions

Intervention 1: Intervention group: The jujube fruit with the scientific name Ziziphus jujuba is identified after purchase from the medicinal plant centers of Birjand city and 100 grams of dried seedl

Eligibility

Sex/Gender

All

Age

30 Years to 60 Years

Inclusion criteria

Inclusion criteria: Willingness to participate in the study Having systolic blood pressure above 14 and diastolic above 8, confirmed and controlled by a doctor for at least one year Elevation of at least one lipid profile parameter

Exclusion criteria

Exclusion criteria: Having other cardiovascular diseases Pregnancy Breastfeeding

Design outcomes

Primary

Measure	Time frame
Cholesterol. Timepoint: At the beginning of the study (before the start of the intervention) and 4 and 8 weeks after starting jujube syrup consumption. Method of measurement: Blood test.	—

Secondary

Measure	Time frame
Triglycerides. Timepoint: ?At the beginning of the study (before the start of the intervention) and 4 and 8 weeks after starting jujube syrup consumption. Method of measurement: Blood test.;Low-density lipoprotein. Timepoint: ?At the beginning of the study (before the start of the intervention) and 4 and 8 weeks after starting jujube syrup consumption. Method of measurement: Blood test.;High-density lipoprotein. Timepoint: ?At the beginning of the study (before the start of the intervention) and 4 and 8 weeks after starting jujube syrup consumption. Method of measurement: Blood test.;Malondialdehyde. Timepoint: ?At the beginning of the study (before the start of the intervention) and 4 and 8 weeks after starting jujube syrup consumption. Method of measurement: Blood test.;Glutathione. Timepoint: ?At the beginning of the study (before the start of the intervention) and 4 and 8 weeks after starting jujube syrup consumption. Method of measurement: Blood test.	—

Measure

Time frame

Triglycerides. Timepoint: ?At the beginning of the study (before the start of the intervention) and 4 and 8 weeks after starting jujube syrup consumption. Method of measurement: Blood test.;Low-density lipoprotein. Timepoint: ?At the beginning of the study (before the start of the intervention) and 4 and 8 weeks after starting jujube syrup consumption. Method of measurement: Blood test.;High-density lipoprotein. Timepoint: ?At the beginning of the study (before the start of the intervention) and 4 and 8 weeks after starting jujube syrup consumption. Method of measurement: Blood test.;Malondialdehyde. Timepoint: ?At the beginning of the study (before the start of the intervention) and 4 and 8 weeks after starting jujube syrup consumption. Method of measurement: Blood test.;Glutathione. Timepoint: ?At the beginning of the study (before the start of the intervention) and 4 and 8 weeks after starting jujube syrup consumption. Method of measurement: Blood test.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactReza Mohebbati

Gonabad University of Medical Sciences

mohebbatir@gmail.com+98 51 5722 3028

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026