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Comparison of the effect of intravenous paracetamol (Apotel) and dexamethasone in the relief of acute migraine headaches

Comparison of the effect of intravenous paracetamol (Apotel) and dexamethasone in the relief of acute migraine headaches referred to the emergency department

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20240619062184N1
Enrollment
80
Registered
2024-07-11
Start date
2024-07-22
Completion date
Unknown
Last updated
2024-07-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute migraine headache. Cluster headache syndrome, unspecified

Interventions

Intervention 1: Intervention group A: receiving interavenous paracetamol with a dose 1 gram .The length of the study period is one year and each drug is injected once. Intervention 2: Intervention gro

Sponsors

Birjand University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: Not having a specific neurological disease No history of continuous use of drugs and long-term painkillers

Exclusion criteria

Exclusion criteria: pregnancy History of neurological disease Patients without personal consent Having a body temperature higher than37.7 degrees Celsius Having a diastolic blood pressure greater than 105 mm Hg Patients treated with systemic corticosteroids Allergy to dexamethasone, egg and soy Patients with a history of diabetes mellitus Active gastrointestinal ulcers Myocardial infarction in the previous week Hypokalemic familial paralysis (for dexamethasone) Continuous use of drugs and long-term painkillers

Design outcomes

Primary

MeasureTime frame
Pain reduction in acute migraine headache patients based on Visual pain measurement criteria. Timepoint: When the patient enters the study. Method of measurement: Visual pain measurement criteria.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactHashem Mirbolooki

Birjand University of Medical Sciences

hashemmirbolooki@gmail.com+98 56 3162 6000

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026