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Effect of Cuscuta chinensis on depression

Effect of Cuscuta chinensis on minor to moderate depression in patients referred to psychiatry clinic

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
IRCT
Registry ID
IRCT20240619062173N1
Enrollment
90
Registered
2024-09-14
Start date
2020-02-19
Completion date
Unknown
Last updated
2025-01-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Condition 1: Mild depression. Condition 2: moderate depression. Major depressive disorder, single episode, mild Bipolar disorder, current episode depressed, moderate

Interventions

Intervention 1: Intervention group: In addition to the routine treatment of fluoxetine 20 mg daily, Cuscuta chinensis extract powder (1.2 g) along with milk on an empty stomach. In this research, the
a sample was kept at the Herbarium for future referenc. The aquoues extract was prepared by heating the macerated plant at 90 °C in water for 15 minutes. Using spary dryer, the extract was dried into

Sponsors

Rafsanjan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
20 Years to 65 Years

Inclusion criteria

Inclusion criteria: age 20-65 year Diagnosis of mild to moderate depression by a neurologist with a Beck score of 10 to 30 Complete the informed consent form

Exclusion criteria

Exclusion criteria: Patients with other mental disorders such as schizophrenia, schizoaffective disorder, bipolar disorder, psychotic disorder Physical disorder that directly leads to depression (hypothyroid, pregnancy and breastfeeding, drug addicts) Patients with suicidal thoughts Patients in need of ECT (Electro Canvulse Therapy) Allergic reactions to plants of the Cuscuta epithymum family Beck score higher than 30 Alcohol abuse diagnosed cancer

Design outcomes

Primary

MeasureTime frame
Beck's Depression Inventory score. Timepoint: Completing the Beck's Depression Inventory at the beginning of the study, 3 weeks and 6 weeks after intervention. Method of measurement: Beck's Depression Inventory.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactGholamreza Bazmandegan

Rafsanjan University of Medical Sciences

bkhrbster@gmail.com+98 34 3428 0185

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026