type 1 diabetic. Type 1 diabetes mellitus
Conditions
Interventions
Intervention 1: Intervention group: Patients are given 1 BioDiab capsule from TAKGENE Company containing strains of Lactobacillus acidophilus, Lactobacillus casei, Bifidobacterium lactis, Bifidobacter
Sponsors
Mashhad University of Medical Sciences
Eligibility
Sex/Gender
All
Age
6 Years to 18 Years
Inclusion criteria
Inclusion criteria: Children aged 6 to 18 years with type 1 diabetes, at least two years have passed since the onset of diabetes. 10% = HbA1c HbA1c = 6.5%
Exclusion criteria
Exclusion criteria: Patients with kidney, Gastrointestinal, Respiratory disease. Type 1 diabetic patients who have a history of taking anti-inflammatory drugs, antibiotics, or immunosuppressive drugs during the month before the start of the study. Type 1 diabetic patients who have a history of consuming products containing probiotics, prebiotics or antioxidants during the month before the start of the study. Patients who have a history of participation in similar plans of probiotic effect in blood sugar control.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| High-sensitivity C-reactive Protein (hs CRP). Timepoint: At the beginning of the study, at the end of the 3rd, 6th and 9th months. Method of measurement: Enzyme-linked immuno_sorbent assay (ELIZA).;Hemoglobin A1C (HbA1c). Timepoint: At the beginning of the study, at the end of the 3rd, 6th and 9th months. Method of measurement: Fluorescence Immuno. | — |
Secondary
| Measure | Time frame |
|---|---|
| Blood pressure (Bp). Timepoint: At the beginning and end of the study. Method of measurement: Dial sphygmomanometer.;Thyroid-Stimulating Hormone (TSH). Timepoint: At the beginning and end of the study. Method of measurement: Enzyme-linked immuno_sorbent assay (ELIZA).;Thyroxine (T4). Timepoint: At the beginning and end of the study. Method of measurement: Enzyme-linked immuno_sorbent assay (ELIZA). | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactZahra Orouji Boroujeni
Mashhad University of Medical Sciences
Outcome results
None listed