effectiveness of phenytoin and Levetiracetam and valproic acid in prevention of seizure of brain hemorrahage

Comparison of the effectiveness of phenytoin and Levetiracetam and valproic acid in prevention of seizure of post traumatic brain hemorrahage

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20240617062155N1

Enrollment

225

Registered

2024-08-10

Start date

2024-08-01

Completion date

Unknown

Last updated

2024-08-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

traumatic intracerebral haemorrhage. Focal traumatic brain injury

Interventions

Intervention 1: Intervention group 1: In this group, the patients are treated with the anticonvulsant drug phenytoin (Caspian-Iran) with a loading dose of 20 mg/kg and injection within one hour and a

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Head trauma requiring prophylactic anticonvulsant treatment

Exclusion criteria

Exclusion criteria: Pregnancy History of epilepsy Allergy to the studied drugs

Design outcomes

Primary

Measure	Time frame
Seizure. Timepoint: The first day to a week after starting the study. Method of measurement: Clinical observation.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactBenyamin Beyrami

Arak University of Medical Sciences

benyamin.medicine@gmail.com+98 86 3314 4712

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026