Refractory epilepsy. Epilepsy, unspecified, intractable, without status epilepticus
Conditions
Interventions
Intervention group:This intervention is conducted in patients based on the history and clinical examination of seizures and confirmed in the ideal state of the brain EEG. The method of working is that
Sponsors
Shahid Beheshti University of Medical Sciences
Eligibility
Sex/Gender
All
Age
3 Months to 14 Years
Inclusion criteria
Inclusion criteria: Children who based on history and physical examination and electroencephalogram have epilepsy syndromes such as Infantile spasm, Landau-Kleffner syndrome, seizure disorders with waves like hypsarrythmia or burst suppression pattern
Exclusion criteria
Exclusion criteria: Fever leukocytosis high ESR and CRP positivity of blood culture positivity of covid PCR test unknown metabolic disorders positive PPD test, age under 2 months or age over 15 years cases where corticosteroid use is contraindicated
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The changes and improvement of EEG before and after receiving methylprednisolone pulse. Timepoint: before the start of the intervention and one day after receiving the intervention and 6, 12, 18, 24 months after the intervention. Method of measurement: Questionnaire and reading and comparison of EEGs by a specialist in pediatric neurology and a specialist in pediatric neurology and electrophysiology and epilepsy fellowship. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactKhatereh Bagheramiri
Shahid Beheshti University of Medical Sciences
Outcome results
None listed