Studying the effect of targeted fluid therapy on renal outcomes following major vascular surgery

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20240612062095N2

Enrollment

100

Registered

2026-02-18

Start date

2026-06-12

Completion date

Unknown

Last updated

2026-06-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Studying the effect of targeted fluid therapy on renal outcomes following major vascular surgery.

Interventions

Intervention 1: Intervention group:Patients who are candidates for major vascular surgery:Target group: A noninvasive cardiac output monitor should be applied immediately. Maintain SVV = 13% and a MAP

Eligibility

Sex/Gender

All

Age

18 Years to 70 Years

Inclusion criteria

Inclusion criteria: Adult patients (=18 years) Scheduled for elective, non-traumatic major lower extremity vascular surgery (infra-inguinal arterial bypass or major amputation for vascular insufficiency) Planned for neuraxial anesthesia.

Exclusion criteria

Exclusion criteria: Pre-existing end-stage renal disease requiring chronic dialysis Advanced CKD (eGFR <20 mL/min/1.73m²) Emergency surgery Severe aortic or mitral valve stenosis Pregnancy

Design outcomes

Primary

Measure	Time frame
Incidence of AKI within 72 hours post-surgery, defined by the KDIGO serum creatinine criteria. Timepoint: It will be checked and recorded at 0, 24, 48 and 72 hours after the operation. Method of measurement: Serum Creatinine Analyzer Device.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactFatemeh Javaherforooshzadeh

Ahvaz University of Medical Sciences

javaherforoosh-f@ajums.ac.ir+98 916 111 4831

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Jun 11, 2026