The effect of Metin drug on drug consumption in patients undergoing orthopedic surgery

The effect of memantine drug on opioid consumption in patients undergoing orthopedic surgery hospitalized in the intensive care unit

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20240612062095N1

Enrollment

Registered

2024-06-16

Start date

2024-06-20

Completion date

Unknown

Last updated

2024-06-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

The effect of the drug Mamantine. Adverse effect of other drugs, medicaments and biological substances, initial encounter

Interventions

Intervention group: Patients undergoing orthopedic surgery are hospitalized in the intensive care unit, so that after entering the intensive care unit and fully awake, memantine tablets 5 mg twice a d

Eligibility

Sex/Gender

All

Age

21 Years to 56 Years

Inclusion criteria

Inclusion criteria: patients of both sexes 21 to 56 years physical condition Physical American Society of Anesthesiologists (ASA) I and II) who undergo orthopedic surgery

Exclusion criteria

Exclusion criteria: Patients with diabetes Heart disease high blood pressure Chronic obstructive respiratory disease Coagulation abnormalities ???????? ??? ???? ????? Patients who are allergic to study drugs

Design outcomes

Primary

Measure	Time frame
Pain score using visual analog scale (VAS). Timepoint: It will be checked and recorded at 6, 8, 24, 36 and 48 hours after the operation. Method of measurement: After surgery.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactKamran Mahmoodi

Ahvaz University of Medical Sciences

mahmoudi-k@ajums.ac.ir+98 913 381 3875

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026