Skip to content

Comparison of the effect of strengthening exercises and Intermittent Pneumatic Compression (IPC) in diabetes mellitus

Comparison of the effect of strengthening exercises and Intermittent Pneumatic Compression (IPC) application on nitric oxide serum level and quality of life in people with type 2 diabetes neuropathy

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT20240611062084N1
Enrollment
20
Registered
2024-08-07
Start date
2024-08-05
Completion date
Unknown
Last updated
2024-08-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Diabetes type 2 neuropathy. Type 2 diabetes mellitus with neurological complications

Interventions

Intervention 1: Intervention group: Strength training group using weights to resist the movements of the lower limbs. Intervention 2: Intervention group: The intermittent pneumatic compression group u

Sponsors

Tarbiat modares university
Lead Sponsor

Eligibility

Sex/Gender
All
Age
45 Years to 65 Years

Inclusion criteria

Inclusion criteria: Score greater than or equal to 7 in the Michigan questionnaire BMI between 18.5 and 29.9 Score of at least 3 in knee and ankle muscles Getting a score less than 13 in the Timed up and Go walking test Approval of the written consent form to participate in the study Not having a regular exercise program (at least 30 minutes a day and 3 days a week) in the last year Not any physiotherapy interventions apply in the last three months The absence of any lower limb disorders that lead to the inability to perform the treatment process (such as skin problems, acute joint and muscle problems, etc.) Absence of having orthopedic and neurological diseases such as stroke, cerebral palsy, poliomyelitis, rheumatoid arthritis, prosthesis, etc. Absence of severe cardiovascular disease such as arterial and venous ulcers and acute heart disease, cardiac autonomic arrhythmia Absence of diabetic foot ulcer Absence of severe unstable proliferative retinopathy Absence of acute kidney injury requiring hemodialysis People's blood pressure should be in the range of 110/70 to 140/90 The amount of controlled FBS before interventions should be between 100 and 180 Hemoglobin glycolysis (HbA1c) less than 9 and at least 6.5

Exclusion criteria

Exclusion criteria: The patient's unwillingness to continue cooperation The appearance of symptoms of autonomic instability Occurrence of any unforeseen problems in patients

Design outcomes

Primary

MeasureTime frame
Blood serum nitric oxide level. Timepoint: Measurement of blood serum nitric oxide before the intervention and after the intervention course. Method of measurement: Blood serum nitric oxide detection kit.;Quality of life questionnaire score. Timepoint: Quality of life questionnaire scores before the intervention and after the intervention course. Method of measurement: SF 36 quality of life questionnaire.

Secondary

MeasureTime frame
6 minutes walking test. Timepoint: Measuring the length of a person's walking path in six minutes before the intervention and after the end of the intervention period. Method of measurement: Using a standard meter to measure the length of the navigation path.;Tandem stance test. Timepoint: Measurement of standing time in tandem position before the intervention and after the end of the intervention period. Method of measurement: Using a stopwatch to measure time.;Timed get up and go test. Timepoint: Measuring the time of getting up and go before the start of the intervention and after the end of the intervention period. Method of measurement: Using a stopwatch to measure time.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMohammad jafar Zibaee bani

Tarbiat modares university

zibaee.mj@modares.ac.ir+98 21 8288 2009

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026