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Comparison of the effects of oral capsule of mefenamic acid and oral capsule of Humulus lupulus plant extract on primary dysmenorrhea

Comparison of the effects of oral capsule of mefenamic acid and oral capsule of Humulus lupulus plant extract on primary dysmenorrhea

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20240609062056N1
Enrollment
100
Registered
2024-11-19
Start date
2024-11-21
Completion date
Unknown
Last updated
2025-01-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Dysmenorrhea is not considered a disease, it is a type of normal pain, which is why the ICD-10 code was not entered..

Interventions

Intervention 1: Intervention group: The intervention group will receive capsules containing rue plant, purchased from reputable herbalists in Tehran. The flower parts of the plant will be powdered and

Sponsors

Shahid Beheshti University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 30 Years

Inclusion criteria

Inclusion criteria: Participants should be in the age range of 18 to 30 They should be Iranian They should not have any known chronic diseases They should not have taken any medication for three months prior to the intervention. They should not have symptoms such as burning, itching, or abnormal vaginal and cervical secretions They should have regular cycles of 22 to 35 days Body mass index (BMI) should be between 18.5 to 26 They should have experienced primary dysmenorrhea in the past 6 months based on the visual analog scale They should be students residing in Al-Zahra Girls' Dormitory of Shahid Beheshti University of Medical Sciences in Tehran. The duration of bleeding should be between 3 to 7 days There should be no bleeding between menstruation There should be no occurrence of stressful events such as the death of relatives or surgery in the last 6 months They should not smoke or consume alcohol

Exclusion criteria

Exclusion criteria: Participants consuming any herbal medications during the study. Participants expressing unwillingness to continue treatment Onset of kidney or liver disease or any condition requiring discontinuation of treatment according to the physician's opinion during the study Improper use of chamomile extract capsules or mefenamic acid, or consumption of less than 7 capsules in the first three days of menstruation Take any non-sterodiol non-inflammatory drug other than mefenamic acid more than 3 times a day

Design outcomes

Primary

MeasureTime frame
Primary Dysmenorrhea. Timepoint: Investigation of dysmenorrhea with a pain ruler at the beginning of the study (befor the start of the intervention) and cycles 1 and 2 after taking oral capsules of hop plant and oral capsules of mefenamic acid. Method of measurement: Visual Analog Scale.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Seyedeh Hanieh Alamolhoda

Shahid Beheshti University of Medical Sciences

Alamolhoda.h@gmail.com+98 21 8865 5366

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026