Heart failure caused by treatment with anthracyclines. ????????????? ???? ?? ???? ??????? ???? ?????? ???? ???????????? ??
Conditions
Interventions
Intervention 1: Intervention group: 28 patients were treated with bisoprolol 1/25 mg (from MERCK company BRAND NAME CONCOR)at the begining and the optimize the drug dose until 2/5 mg per day with cont
8 patients were excluded due to non compliance at first the intervention group include 35 patients.and echo cardiography was done at the begining and 6 mouths after termination of chemotherapy. Interv
Sponsors
Iran University of Medical Sciences
Eligibility
Sex/Gender
All
Age
40 Years to No maximum
Inclusion criteria
Inclusion criteria: cancer patients treated with anthracyclines LVEF>45 % not using other drugs for heart problems
Exclusion criteria
Exclusion criteria: known case of heart disease LVEF less than 45 percent age below 40
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Systolic function in TTE. Timepoint: before starting the study ,and then 6 mouths after the end of the chemotherapy. Method of measurement: LV systolic function in TTE by Simpson method.;Diastolic Lv function. Timepoint: at the begining ,and then 6 mouths after the end of chemotherapy. Method of measurement: LV diastolic function in TTE.;LV global longitudinal strain by strain echocardiography. Timepoint: at the begining ,and the 6 mouths after the end of chemotherapy. Method of measurement: by strain echocardiography. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public Contactmah hedayati emami
Iran University of Medical Sciences
Outcome results
None listed