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the effect of vitamin D in the treatment of chemotherapy-induced fever and neutropenia in children with malignancy

Evaluation of the effect of vitamin D in the treatment of chemotherapy-induced fever and neutropenia in children with malignancy

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20240608062045N1
Enrollment
100
Registered
2024-07-22
Start date
2022-12-22
Completion date
Unknown
Last updated
2024-08-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Fever and neutropenia.

Interventions

Intervention group: Routine treatment group for fever and neutropenia (ceftazidime and amikacin) + vitamin D oral drops with a dose of 1000 units daily for two weeks.

Sponsors

Arak University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
1 Years to 16 Years

Inclusion criteria

Inclusion criteria: pediatric hematology and oncology department of Amirkabir Arak Hospital, aged 1 to 16 years, with fever and neutropenia due to chemotherapy, informed consent of the patient's parents for the child to participate in the study, the initial vitamin D level is lower than the normal level) by the initial vitamin D level test D is measured and values ??less than 20 ng/ml are considered as deficiency and values ??of 29 ng/ml are considered as insufficient.) Not taking vitamins arbitrarily

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Fever and neutropenia. Timepoint: For each patient on the 3rd, 7th, 10th, 14th day, the results are recorded as full treatment, partial treatment or no treatment. Method of measurement: The level of neutropenia is checked by the CBC test, which is routinely taken every other day from hospitalized patients, and The degree of fever is also recorded by the ward nurse with a thermometer.

Countries

Iran (Islamic Republic of)

Contacts

Public Contactsara atoufi najaf abadi

Arak University of Medical Sciences

dr.atoufi77@gmail.com+98 86 3417 3507

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026