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Evaluating the effect of NeoPUTTY as an apical plug used in 6th tooth of lower jaw in postoperative pain

Evaluating the effect of NeoPUTTY as an apical plug used in mandibular first molar in postoperative pain and flare up; a randomized clinical trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT20240607062028N1
Enrollment
30
Registered
2024-08-28
Start date
2024-11-05
Completion date
Unknown
Last updated
2024-09-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Flare-up and pain. Chronic apical periodontitis

Interventions

Intervention 1: Intervention group: NeoPUTTY (Avalon Biomed Inc., Bradenton, USA). A bioceramic, bioactive MTA is premixed in a syringe. This material is placed at the apical end of the roots as a plu

Sponsors

Mashhad University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
6 Years to 15 Years

Inclusion criteria

Inclusion criteria: Patients in the age range of 6 to 15 years Necrotic immature mandibular first molar with open apex (size 60 to 100) A tooth with chronic apical periodontitis with the presence of a radiolucency greater than 3 mm2 in periapical radiography Tooth without sinus tract, no drainage from the canal, no swelling and no acute apical periodontitis Patients should not have pain in the area of ??the target tooth before starting the root canal treatment Patients should have not received any medical treatment before starting the root canal treatment Teeth without root deviation, root resorption or calcification Tooth without previous root canal treatment or crown Teeth without any root fracture or craze lines

Exclusion criteria

Exclusion criteria: Necrotic immature mandibular first molar with open apex (larger than size 100) Teeth with root fracture, craze lines, root deviation, resorption or calcifications lack of child cooperation Teeth with compromised periodontal structure, severe mobility Teeth with previous root canal treatment, post or crown Teeth with open apex and severe destruction that are unrestorable Patient unwillingness to participate Major systemic disease (ASA 3 or higher) The patient's severe pain that led to the use of analgesic

Design outcomes

Primary

MeasureTime frame
Flare-up and pain. Timepoint: 3, 6, 12, 24, 48 and 72 hours postoperative. Method of measurement: Visual Analogue Scale.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMaryam Khorasanchi

Mashhad University of Medical Sciences

khorasanchim4011@mums.ac.ir+98 915 119 9667

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026