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The effect of dietary probiotics combined with conventional therapy in the treatment of seborrheic dermatitis of the scalp

Comparison of the effectiveness of Oral Probiotic with conventional treatment and conventional treatment alone in the treatment of seborrheic dermatitis of the scalp

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT20240604062002N3
Enrollment
64
Registered
2025-07-25
Start date
2025-08-23
Completion date
Unknown
Last updated
2025-08-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Seborrheic dermatitis of the scalp. Seborrheic dermatitis

Interventions

Intervention 1: Intervention group: Daily intake of one oral probiotic capsule for 30 days along with conventional treatment similar to the control group. Each probiotic capsule contains a total of 10

Sponsors

Tabriz University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Patients aged 18-65 years with seborrheic dermatitis of the scalp who referred to the dermatology clinic of Sina Hospital, Tabriz in 1404. Patient consent to participate in this study

Exclusion criteria

Exclusion criteria: Use of antifungal or corticosteroid drugs (topical or systemic) or complementary drugs including probiotics Use of antibiotics in the last month or during the study period Immune system deficiency due to hereditary or underlying disease or use of immunosuppressive drugs Women who are breastfeeding, pregnant or intending to become pregnant at the time of the study Failure to complete the treatment course by the patient due to low compliance, occurrence of side effects or unwillingness of the patient to continue participating in the study

Design outcomes

Primary

MeasureTime frame
Severity of seborrheic dermatitis of the scalp. Timepoint: The forth week, the sixth week. Method of measurement: Zhang et al.'s 16-point scale.;Patient satisfaction. Timepoint: The forth week, the sixth week. Method of measurement: VAS score.;Adverse effects of treatment. Timepoint: The forth week, the sixth week. Method of measurement: Clinical assessment.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactFaegheh Sheikhalizadeh Noubar

Tabriz University of Medical Sciences

sheikhalizadehf@tbzmed.ac.ir+98 41 3335 5921

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026