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The effect of using tofacitinib with phototherapy in patients with vitiligo

Investigating the effect of using the combination of tofacitinib with phototherapy in comparison to phototherapy in vitiligo patients referred to Sinai Hospital in Tabriz

Status
Recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT20240604062002N2
Enrollment
35
Registered
2025-03-13
Start date
2025-04-04
Completion date
Unknown
Last updated
2025-07-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

vitiligo. Vitiligo

Interventions

Intervention 1: Intervention group: First intervention: consisting of 19 patients who underwent 20 phototherapy sessions. Intervention 2: Intervention group: Second intervention: consisting of 16 pati

Sponsors

Tabriz University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: Definite diagnosis of vitiligo Vitiligo Disease Activity (VIDA) greater than one Not having received any topical or systemic immunosuppressive therapy in the six months prior to study entry Were candidates for phototherapy

Exclusion criteria

Exclusion criteria: Patients with a history of known malignancy, HIV or hepatitis B or C positive Patients with leukopenia or anemia, Patients with renal or hepatic insufficiency, Patients with peptic ulcer disease, Patients using immunosuppressive drugs (prednisone, methotrexate, mycophenolate mofetil, cyclosporine or TNH-alpha inhibitors), Pregnant or lactating women

Design outcomes

Primary

MeasureTime frame
Treatment effectiveness. Timepoint: Before the study, first month, second month, third month, fourth month. Method of measurement: VASI score and VIDA score.;Patient satisfaction. Timepoint: Before the study, first month, second month, third month, fourth month. Method of measurement: VAS: Visual analogue Scale.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactFaegheh Sheikhalizadeh Noubar

Tabriz University of Medical Sciences

sheikhalizadehf@tbzmed.ac.ir+98 41 3335 5921

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026