Effect of Fucoidan and Fucoxanthin on Improving Athletic Performance

Effects of fucoidan and fucoxanthin supplementation on athletic performance, recovery, and oxidative stress markers in endurance and strength athletes

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20240603061995N1

Enrollment

Registered

2025-05-13

Start date

2025-06-22

Completion date

Unknown

Last updated

2025-07-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Oxidative stress

Interventions

Intervention 1: Intervention Group 1: Fucoidan: One 500 mg fucoidan capsule (brown algae polysaccharide, 85% purity, Maritech, Australia) daily, taken orally with breakfast for 8 weeks. Standardized d

Eligibility

Sex/Gender

Male

Age

20 Years to 35 Years

Inclusion criteria

Inclusion criteria: At least 3 years of regular training in endurance or strength disciplines Age range: 20 to 35 years Commitment to adhering to the training program, diet, and intervention protocol Gender: Male

Exclusion criteria

Exclusion criteria: Having chronic diseases (diabetes, cardiovascular diseases) Use of antioxidant supplements in the past 3 months

Design outcomes

Primary

Measure	Time frame
Malondialdehyde (MDA). Timepoint: Baseline (Week 0) and Post-intervention (Week 8). Method of measurement: Serum MDA levels are measured using the TBARS assay (Cayman Chemical, USA) and a spectrophotometer (Shimadzu UV-1800, Japan) at 532 nm, reported as nmol/mL.;Superoxide dismutase (SOD). Timepoint: Baseline (Week 0) and Post-intervention (Week 8) (Measured in fasted state, morning). Method of measurement: Serum SOD activity is measured using a colorimetric assay (Cayman Chemical, USA) and a spectrophotometer (Shimadzu UV-1800, Japan) at 440 nm, reported as U/mL.;Glutathione peroxidase (GPx). Timepoint: Baseline (Week 0) and Post-intervention (Week 8) (Measured in fasted state, morning). Method of measurement: Serum GPx activity is measured using a kinetic assay (Sigma-Aldrich, USA) and a spectrophotometer (Shimadzu UV-1800, Japan) at 340 nm, reported as nmol/min/mL.	—

Measure

Time frame

Malondialdehyde (MDA). Timepoint: Baseline (Week 0) and Post-intervention (Week 8). Method of measurement: Serum MDA levels are measured using the TBARS assay (Cayman Chemical, USA) and a spectrophotometer (Shimadzu UV-1800, Japan) at 532 nm, reported as nmol/mL.;Superoxide dismutase (SOD). Timepoint: Baseline (Week 0) and Post-intervention (Week 8) (Measured in fasted state, morning). Method of measurement: Serum SOD activity is measured using a colorimetric assay (Cayman Chemical, USA) and a spectrophotometer (Shimadzu UV-1800, Japan) at 440 nm, reported as U/mL.;Glutathione peroxidase (GPx). Timepoint: Baseline (Week 0) and Post-intervention (Week 8) (Measured in fasted state, morning). Method of measurement: Serum GPx activity is measured using a kinetic assay (Sigma-Aldrich, USA) and a spectrophotometer (Shimadzu UV-1800, Japan) at 340 nm, reported as nmol/min/mL.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactMorteza Jourkesh

Islamic Azad University

ilkhchi@cms.iau.ir04133421214-7

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026