Studying the effect of ketoconazole on fungal infections

Comparison of the effectiveness of intravenous fluconazole with and without ketoconazole shampoo bath in preventing fungal infection in premature infants in the neonatal intensive care unit: A randomized clinical trial

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20240602061980N3

Enrollment

Registered

2025-10-18

Start date

2025-10-12

Completion date

Unknown

Last updated

2025-12-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Fungal infection.

Interventions

Intervention 1: Intervention group: There are babies who are washed with 2% ketoconazole shampoo twice a week in addition to routine treatment. Intervention 2: Control group: Infants receiving routine

Eligibility

Sex/Gender

All

Age

1 Days to No maximum

Inclusion criteria

Inclusion criteria: Birth weight less than 1500 g

Exclusion criteria

Exclusion criteria: Skin lesion

Design outcomes

Primary

Measure	Time frame
Fungal infection. Timepoint: During hospitalization. Method of measurement: checklist.	—

Secondary

Measure	Time frame
Reducing the length of hospitalization. Timepoint: During hospitalization. Method of measurement: checklist.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSamira Puornajaf

Babol University of Medical Sciences

samirapournajaf@yahoo.com+98 11 3223 8301

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026