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Investigating the effect of Pistacia atlantica cream in the treatment of wounds in diabetic patients

Investigating the effect of Pistacia atlantica cream in the treatment of wounds in diabetic patients, a double-blind clinical study

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20240601061969N1
Enrollment
50
Registered
2024-06-21
Start date
2024-08-05
Completion date
Unknown
Last updated
2024-06-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

diabetic.

Interventions

Intervention 1: Antibiotic treatment with 25% Pistacia atlantica cream. Intervention 2: Antibiotic treatment for diabetic ulcer with mupirocin cream.

Sponsors

Fasa University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
20 Years to 55 Years

Inclusion criteria

Inclusion criteria: Patients with diabetic foot ulcers aged between 20 and 55 years old (at most 2 weeks have passed since the onset of the ulcer) The patient's blood sugar should be under control, the blood sugar should be below 7.5 for three months Having diabetic foot ulcers without osteomyelitis (having various ulcers on the right or left foot with moderate inflammation that has not reached the stage of osteomyelitis) Not using corticosteroids and immunosuppressive drugs Wound with Wegener grade 2 Ulcers in the lower limbs Not having a history of allergy to medicinal plants Having no history of liver and heart disease, pregnancy and pregnancy, porphyria and lupus malignancy No history of surgery in the last 6 months Hemodynamically stable

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Wound size. Timepoint: the beginning of the study (before the start of the intervention); 3; 5; 9; 13; 17; 21; 25; 30 days after starting to use the cream. Method of measurement: ruler.;Infection. Timepoint: the beginning of the study (before the start of the intervention); 3; 5; 9; 13; 17; 21; 25; 30 days after starting to use the cream. Method of measurement: Clinical examination.;Type of secretions. Timepoint: the beginning of the study (before the start of the intervention); 3; 5; 9; 13; 17; 21; 25; 30 days after starting to use the cream. Method of measurement: Clinical examination.;The amount of secretions. Timepoint: the beginning of the study (before the start of the intervention); 3; 5; 9; 13; 17; 21; 25; 30 days after starting to use the cream. Method of measurement: Clinical examination.;Hospitalization day. Timepoint: the beginning of the study (before the start of the intervention); 3; 5; 9; 13; 17; 21; 25; 30 days after starting to use the cream. Method of measurement: Clinical examination.;Background disease. Timepoint: the beginning of the study (before the start of the intervention); 3; 5; 9; 13; 17; 21; 25; 30 days after starting to use the cream. Method of measurement: Clinical examination.;Redness of the wound. Timepoint: the beginning of the study (before the start of the intervention); 3; 5; 9; 13; 17; 21; 25; 30 days after starting to use the cream. Method of measurement: Clinical examination.;Edema. Timepoint: the beginning of the study (before the start of the intervention); 3; 5; 9; 13; 17; 21; 25; 30 days after starting to use the cream. Method of measurement: Clinical examination.;Bruising around the wound. Timepoint: the beginning of the study (before the start of the intervention); 3; 5; 9; 13; 17; 21; 25; 30 days after starting to use the cream. Method of measurement: Clinical examination.;Being warm around. Timepoint: the beginning of the study (before the start of the intervention); 3; 5; 9; 13; 17; 21; 25; 30 days after starting to

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSara Shafiee Bidshahi

Fasa University of Medical Sciences

e.jahantab@fasau.ac.ir+98 71 5331 6300

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026