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Investigating the prophylactic effect of probiotics on diarrhea in liver transplant recipient

Investigating the prophylactic effect of probiotics on diarrhea in liver transplant recipient

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20240530061953N1
Enrollment
60
Registered
2024-07-15
Start date
2024-08-22
Completion date
Unknown
Last updated
2024-07-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Condition 1: liver transplant. Condition 2: diarrhea. Condition 3: infection. Condition 4: liver transplant complication. Liver transplant status Other complications of liver transplant Liver transplant infection Unspecified complication of liver transplant

Interventions

Intervention 1: Intervention group: Patients in this group will use a probiotic supplement from Zist Takhmir (Lactocare), taking two capsules daily. The administration of this medication will commence

Sponsors

Tehran University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: age between 17 to 70 years First liver transplant ability to swallow Probiotics

Exclusion criteria

Exclusion criteria: pregnant or lactating mother non liver related Immunosuppressed patient probiotics use within 2 weeks of trial diarrhea in patient before trial history of hypersensitivity or reaction to probiotics

Design outcomes

Primary

MeasureTime frame
Diarrhea in 30 days after liver transplant. Timepoint: every day for 10 days and then weekly. Method of measurement: History and stool exam.

Secondary

MeasureTime frame
Infectious complications after liver transplant. Timepoint: daily for a week then weekly after discharge. Method of measurement: history and physical examination and lab data.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAlireza Abkhoo

Tehran University of Medical Sciences

ar-abkhoo@razi.tums.ac.ir+98 21 6119 5964

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026