Male infertility. Male infertility
Conditions
Interventions
Intervention group: taking grape seed extract tablets for 2 months with a daily dose of two 250 mg tablets. The name of the selected drug is Quetrol Resveratrol from Raha Pharmaceutical Company in a p
Sponsors
Arak University of Medical Sciences
Eligibility
Sex/Gender
Male
Age
20 Years to 45 Years
Inclusion criteria
Inclusion criteria: Sperm parameters are abnormal Not taking other antioxidant drugs by infertile men. the SDFA test (Sperm DNA Fragmentation Assay) shows the presence of fragmented DNA in more than 15% of ejaculated sperm. The age of the patients should be between 20 and 45
Exclusion criteria
Exclusion criteria: Patients with varicocele inflammation of the genital tract or infection men with a history of smoking, alcohol and drug addiction are excluded from the study. Genital tract infection
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Improving the state of sperm parameters (concentration , morphology and motility). Timepoint: At the beginning of the study (before the start of the intervention) and 2 months after the start of taking grapeseed. Method of measurement: Light microscopy and Diff-quick staining.;Reducing the amount of DNA fragmentation. Timepoint: At the beginning of the study (before the start of the intervention) and 2 months after the start of taking grapeseed. Method of measurement: Using the SDFA (Sperm DNA Fragmentation Assay) kit. | — |
Secondary
| Measure | Time frame |
|---|---|
| Side effects. Timepoint: During the intervention. Method of measurement: Follow up. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr. Somayeh Shabib
Arak University of Medical Sciences
Outcome results
None listed