Effectiveness of Repetitive Transcranial Magnetic Stimulation (rTMS) with and without Physical Activity on Depressive Symptoms, Brain Map , Physical Condition and Sleep Quality of Depressed Patients

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20240528061935N1

Enrollment

Registered

2024-06-01

Start date

2024-05-01

Completion date

Unknown

Last updated

2024-06-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Major Depressive Disorder. Major depressive disorder, single episode

Interventions

Intervention 1: Intervention group: They will receive the rTMS protocol in addition to the usual treatment. The research was conducted in such a way that the subjects will be evaluated by the Beck dep

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Minimum literacy to read and write Completing the patients' consent form to participate in the experiment Getting a score above 20 in the Beck depression Inventory No history of special diseases and mental illnesses Not taking psychotropic drugs No drug addiction No history of seizures and epilepsy Have a minimum age of 18 and a maximum age of 65 years

Exclusion criteria

Exclusion criteria: Unwillingness to continue cooperation Failure to complete research questionnaires or filling them incompletely Having intracranial implants (shunts, stimulators, electrodes) and any other metal object near the head

Design outcomes

Primary

Measure	Time frame
Depression. Timepoint: Before and after 25 sessions of intervention. Method of measurement: Beck depression questionnaire is used to check depression.;Quantitative electroencephalography. Timepoint: Before and after 25 sessions of intervention. Method of measurement: Quantitative electroencephalography measurement scale.;Physical Condition. Timepoint: Before and after 25 sessions of intervention. Method of measurement: Lindenberg Physical Status Improvement Questionnaire.;Sleep Quality. Timepoint: Before and after 25 sessions of intervention. Method of measurement: Pittsburgh Sleep Quality Questionnaire.	—

Measure

Time frame

Depression. Timepoint: Before and after 25 sessions of intervention. Method of measurement: Beck depression questionnaire is used to check depression.;Quantitative electroencephalography. Timepoint: Before and after 25 sessions of intervention. Method of measurement: Quantitative electroencephalography measurement scale.;Physical Condition. Timepoint: Before and after 25 sessions of intervention. Method of measurement: Lindenberg Physical Status Improvement Questionnaire.;Sleep Quality. Timepoint: Before and after 25 sessions of intervention. Method of measurement: Pittsburgh Sleep Quality Questionnaire.

—

Secondary

Measure	Time frame
CD3 and CD4 levels. Timepoint: In the intervals before and immediately after receiving repetitive brain magnetic stimulation (rTMS) treatment. Method of measurement: Routine blood sample Test for CD3-CD4 level count.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactFirouze Fadaei Goke

Islamic Azad University, Semnan branch

firoozefadaee1@gmail.com+98 21 5649 3166

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026