Investigating the effect of isotretinoin along with itraconazole in the treatment of skin fungus

Investigating the effect of isotretinoin along with itraconazole in the treatment of patients with dermatophytes

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20240527061914N1

Enrollment

Registered

2025-02-13

Start date

2024-12-12

Completion date

Unknown

Last updated

2025-07-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Dermatophyte (fungal disease). Tinea corporis

Interventions

Intervention 1: Intervention group: treated with itraconazole 100 mg every 12 hours and isotretinoin 20 mg every other day and sertaconazole ointment every 8 hours and shampoo ketoconazole 3 times a w

Eligibility

Sex/Gender

All

Age

12 Years to 60 Years

Inclusion criteria

Inclusion criteria: Patients who have been diagnosed with dermatophyte by Koh test

Exclusion criteria

Exclusion criteria: Under 12 years Over 60 years old pregnant milked Has a history of diabetes Has a history of liver disease Has a history of kidney disease History of alcohol consumption

Design outcomes

Primary

Measure	Time frame
Comparison of the effect of isotretinoin on the treatment of dermatophytes. Timepoint: Examination at the beginning of the study and then monthly until the dermatophyte infection is completely resolved. Method of measurement: Clinical examination.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactHajar Masoomi Farah abadi

Tehran University of Medical Sciences

saramasoomi1376@gmail.com+98 911 329 0091

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026