Obstructive sleep apnea. Obstructive sleep apnea (adult) (pediatric)
Conditions
Interventions
Intervention 1: Intervention group 1 (pilot study): Patients suffering from obstructive sleep apnea receive three puffs in each nostril of a spray containing 10 mg/ml furosemide every 8 hours for 30 d
Sponsors
Birjand University of Medical Sciences
Eligibility
Sex/Gender
All
Age
5 Years to No maximum
Inclusion criteria
Inclusion criteria: Patients with a history of sleep disorder and nocturnal snoring and frequent night awakenings and daily fatigue or uncontrolled blood pressure that is mentioned in the history of sleep apnea The number of obstructive apneas greater than five per hour Stop-Bang test score of 4 or more Have a score of 6 or more on the Petersburg Sleep Questionnaire
Exclusion criteria
Exclusion criteria: Acute renal and liver disease Pregnancy Breastfeeding Age under 5 years Having cardiac pace maker Hypersensitivity to any drugs Substance abuse History of liver and kidney diseases Having dementia symptoms History of hypokalemia
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Changes in Beck Depression Inventory (BDI). Timepoint: Before, after 45 days of interventions. Method of measurement: Beck Depression Inventory questionnaire.;Changes in Hamilton Anxiety Inventory (HRSA). Timepoint: Before, after 45 days of interventions. Method of measurement: Hamilton Anxiety Inventory questionnaire.;Changes in Pittsburgh Sleep Quality Questionnaire (PSQI). Timepoint: Before, after 45 days of interventions. Method of measurement: Pittsburgh Sleep Quality Questionnaire.;Quality of Life Questionnaire. Timepoint: Before, after 45 days of interventions. Method of measurement: Quality of Life Questionnaire.;Changes in Stop-Bang sleep apnea questionnaire. Timepoint: Before, after 45 days of interventions. Method of measurement: Stop-Bang sleep apnea questionnaire.;Determining the number of apnea and hypopnea and changes in heart rate and oxygen saturation. Timepoint: Before, after 45 days of interventions. Method of measurement: Determining by using Polysomnography.;Changes in serum levels of CBC? ALT? AST? TSH? Bun? Cr. Timepoint: Before, after 45 days of interventions. Method of measurement: Assay of serum level. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactSeyed Mohammad Mousavi Mirzaei
Birjand University of Medical Sciences
Outcome results
None listed