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An examination of various surgical methods on the complications of cholecystectomy surgery

Comparison of the effect of positional changes and administration of N2O on pain, nausea and vomiting in pneumoperitoneal method with CO2 after laparoscopic cholecystectomy (A double-blind clinical trial study)

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20240526061902N1
Enrollment
126
Registered
2024-06-08
Start date
2024-06-20
Completion date
Unknown
Last updated
2024-06-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pain, nausea, and vomiting after laparoscopic cholecystectomy.

Interventions

Intervention 1: Intervention Group 1: In this group, CO2 gas is removed from the abdomen, and N2O gas is introduced. Intervention 2: Intervention group 2: This group of patients only utilizes Trendele

Sponsors

Yasouj University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: The absence of acute cholecystitis The absence of addiction and substance abuse The absence of drug allergies The absence of mental and psychological disorders The absence of diabetes and systemic diseases according to the ASA score

Exclusion criteria

Exclusion criteria: The presence of severe inflammation and adhesions at the surgical site, necessitating the conversion of laparoscopic surgery to open surgery Rupture of the gallbladder and bile leakage at the surgical site Excessive bleeding during surgery, with the possibility of peritoneal irritation due to the presence of blood in the peritoneum The patient's unwillingness to continue participation in the study after surgery

Design outcomes

Primary

MeasureTime frame
Score of pain in the questionnaire. Timepoint: 6, 12, and 24 hours after the surgery. Method of measurement: On the basis of visual analogue scale (VAS).;Nausea and vomiting. Timepoint: Up to 24 hours after the surgery. Method of measurement: Postoperative Complications Questionnaire.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSeyed Mahdi Ghazanfari

Yasouj University of Medical Sciences

s.mahdighazanfari@gmail.com+98 911 352 3626

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026