investigating the effect of metformin and metformin with myo - inositol on the success of ovulation induction cycles in infertile women with polycystic ovary syndrome

investigating the effect of metformin and metformin with myo - inositol on the success of ovulation induction cycles in infertile women with poly-cystic ovary syndrome

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20240526061897N1

Enrollment

Registered

2024-09-16

Start date

2024-10-22

Completion date

Unknown

Last updated

2025-01-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Infertility. Female infertility

Interventions

Intervention 1: Intervention group: metformin tablet with 1500 mg daily for 3 months plus myoinositol tablet with a dose of 4000 mg or (2000 mg twice a day) daily before breakfast. Intervention 2: Con

Eligibility

Sex/Gender

Female

Age

18 Years to 40 Years

Inclusion criteria

Inclusion criteria: Diagnosed poly-cystic ovary syndrome using the Rotterdam criteria

Exclusion criteria

Exclusion criteria: Suffering from mechanical causes of infertility Husband infertility Current treatment

Design outcomes

Primary

Measure	Time frame
Achieving pregnancy. Timepoint: 4month after begining of the study. Method of measurement: Serum B-HCG.	—

Secondary

Measure	Time frame
The number of ovarian follicles. Timepoint: Day 12 and 16 of the three-month cycle after the start of the study. Method of measurement: Transvaginal ultrasound.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactElahe Mokhtarie

Sabzevar University of Medical Sciences

elahe.mokhtarie@mums.ac.ir+98 51 4401 8424

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026