Investigating the use of radioactive and methylene blue in the results of lymph sampling

Comparing the pathology results of biopsy of sentinel lymph nodes using Mapping vs. standard lymphadenectomy by radioactive material and methylene blue in patients with ovarian masses; a randomized clinical trial

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20240524061882N1

Enrollment

Registered

2024-06-20

Start date

2024-06-27

Completion date

Unknown

Last updated

2024-06-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Ovarian masses. Unspecified ovarian cysts

Interventions

Intervention 1: Intervention group 1: Under the normal membrane of the ovary, methylene blue (a product of Dayaexir company) is injected to visualize the sentinel lymph nodes after anesthesia and befo

Eligibility

Sex/Gender

Female

Age

18 Years to 50 Years

Inclusion criteria

Inclusion criteria: Consent to participate in the study Candidate for ovarian mass surgery ORADs class greater than or equal to 3 Age under 50 years

Exclusion criteria

Exclusion criteria: Allergy to methylene blue History of severe reaction to radioactive material Having an active infection

Design outcomes

Primary

Measure	Time frame
Frequency of sentinel lymph nodes. Timepoint: Only after the intervention will be examined to compare the frequency between the two groups. Method of measurement: Manual prop.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSeyedeh Roghayeh Mirmajidi

Iran University of Medical Sciences

Mirmajidi.s.r@gmail.com+98 26 3448 2864

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026