"Investigating the effect of dexmedetomidine on shivering in caesarean section patients"

A comparative study of the effect of intravenous dexmedetomidine and intrathecal dexmedetomidine on shivering in caesarean section patients under spinal anesthesia

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20240524061880N1

Enrollment

Registered

2025-01-02

Start date

2025-01-19

Completion date

Unknown

Last updated

2025-01-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

shivering in caesarean section patients under spinal anesthesia. Complication of anesthesia during labor and delivery, unspecified

Interventions

Intervention 1: Control group: The control group will be injected with 10 ml of physiological saline during one minute of slow intravenous infusion. Intervention 2: Intervention group: Receiving 0.1 (

Eligibility

Sex/Gender

Female

Age

18 Years to 45 Years

Inclusion criteria

Inclusion criteria: Women with ASA class II who read and accepted the informed consent form

Exclusion criteria

Exclusion criteria: Heart, lung, liver and kidney disease Known history of alcohol or drug use Those who receive vasodilator drugs Need for blood transfusion during surgery

Design outcomes

Primary

Measure	Time frame
Shivering incidence. Timepoint: 0,5,10,15,30,45,60,90(min). Method of measurement: Based on shivering in the patient based on the patient's expression or muscle contraction.;Shivering severity. Timepoint: 0?5?10?15?30?45?60?90(min). Method of measurement: Zero degree: no shivering, Grade 1: Peripheral vasoconstriction, but without visible shivering. Second degree: muscle activity in only one muscle group. Grade 3: Muscle activity in more than one muscle group, but not generalized. Fourth degree: trembling that involves the whole body.	—

Measure

Time frame

Shivering incidence. Timepoint: 0,5,10,15,30,45,60,90(min). Method of measurement: Based on shivering in the patient based on the patient's expression or muscle contraction.;Shivering severity. Timepoint: 0?5?10?15?30?45?60?90(min). Method of measurement: Zero degree: no shivering, Grade 1: Peripheral vasoconstriction, but without visible shivering. Second degree: muscle activity in only one muscle group. Grade 3: Muscle activity in more than one muscle group, but not generalized. Fourth degree: trembling that involves the whole body.

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Secondary

Measure	Time frame
Blood pressures. Timepoint: 0?5?10?15?30?45?60?90(min). Method of measurement: Non invasive couphmetr.;Room temperature. Timepoint: 0?5?10?15?30?45?60?90(min). Method of measurement: E.SUN thermometer.;Core temperature. Timepoint: 0?5?10?15?30?45?60?90(min). Method of measurement: In the inner ear area (using the tympanic membrane thermometer, which is considered the average core temperature and the GENTLE TEMP 520 thermometer from OMRON company).	—

Measure

Time frame

Blood pressures. Timepoint: 0?5?10?15?30?45?60?90(min). Method of measurement: Non invasive couphmetr.;Room temperature. Timepoint: 0?5?10?15?30?45?60?90(min). Method of measurement: E.SUN thermometer.;Core temperature. Timepoint: 0?5?10?15?30?45?60?90(min). Method of measurement: In the inner ear area (using the tympanic membrane thermometer, which is considered the average core temperature and the GENTLE TEMP 520 thermometer from OMRON company).

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactMilad Masaeli

Esfahan University of Medical Sciences

Drmilmas@gmail.com+98 31 3792 9052

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026