Comparing the effectiveness of treatment for obsessive-compulsive disorder

Comparison of the effectiveness of Danger Ideation Reduction Therapy with Exposure and Response Prevention and drug treatment in obsessive-compulsive disorder

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20240523061876N1

Enrollment

Registered

2025-10-29

Start date

2025-08-06

Completion date

Unknown

Last updated

2025-12-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Obsessive-Compulsive Disorder.

Interventions

Intervention 1: Intervention group: Intervention group: The content of the sessions will be conducted over 10 sessions (one 45-minute session per week). DIRT components include six separate therapeuti

Eligibility

Sex/Gender

All

Age

18 Years to 55 Years

Inclusion criteria

Inclusion criteria: Diagnosis of obsessive-compulsive disorder

Exclusion criteria

Exclusion criteria: thoughts or attempting suicide

Design outcomes

Primary

Measure	Time frame
Severity Obsession. Timepoint: Before and after treatment. Method of measurement: Yale-Brown Obsessive-Compulsive Scale(Y-BOCS-II).;Depression. Timepoint: Before and after treatment. Method of measurement: Depression Anxiety Stress Scale(DASS-21).;Anxiety. Timepoint: Before and after treatment. Method of measurement: Depression Anxiety Stress Scale(DASS-21).;Client Engagement. Timepoint: Before and after treatment. Method of measurement: Client Engagement Scale(CES).;Psychological Wellbeing. Timepoint: Before and after treatment. Method of measurement: Ryff Scale Psychological Wellbeing(RSPWB).	—

Measure

Time frame

Severity Obsession. Timepoint: Before and after treatment. Method of measurement: Yale-Brown Obsessive-Compulsive Scale(Y-BOCS-II).;Depression. Timepoint: Before and after treatment. Method of measurement: Depression Anxiety Stress Scale(DASS-21).;Anxiety. Timepoint: Before and after treatment. Method of measurement: Depression Anxiety Stress Scale(DASS-21).;Client Engagement. Timepoint: Before and after treatment. Method of measurement: Client Engagement Scale(CES).;Psychological Wellbeing. Timepoint: Before and after treatment. Method of measurement: Ryff Scale Psychological Wellbeing(RSPWB).

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactPyruz Rezaei

Artesh University of Medical Sciences

pyruzr@yahoo.com+98 21 2248 1806

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026