Investigating the effect of water resistance training and dark chocolate supplementation on On the effective factors in sarcopenia

The effect of eight weeks water resistance training with consumption of dark chocolate on the changes of GDF8, GDF11, ActRIIB, GASP-1 in elderly women

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20240519061840N1

Enrollment

Registered

2024-06-11

Start date

2024-05-16

Completion date

Unknown

Last updated

2024-06-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

The relationship between eight weeks of resistance training in water and consumption of dark chocolate on factors related to sarcopenia in elderly women.

Interventions

Intervention 1: Intervention group 1: Control group: The subjects of this group did not have any sports activities or supplement consumption during this period of eight weeks and continued their norma

Eligibility

Sex/Gender

Female

Age

60 Years to 75 Years

Inclusion criteria

Inclusion criteria: Seniors 60-73 years old and inactive (not participating in regular sports activities in the last 12 months)

Exclusion criteria

Exclusion criteria: Specific diseases such as chronic lung disease - ischemic heart disease - Valvular heart disease - hypertrophic heart failure - smoking - mental and psychological diseases (such as dementia) muscle and joint injuries (such as lumbar disc protrusion)

Design outcomes

Primary

Measure	Time frame
GDF8. Timepoint: 48 hours before the start of the intervention and after the end of the eight weeks of the intervention. Method of measurement: by Realtime -PCR method.;GDF11. Timepoint: 48 hours before the start of the intervention and after the end of the eight weeks of the intervention. Method of measurement: by Realtime -PCR method.;Activin Reseptor IIß. Timepoint: 48 hours before the start of the intervention and after the end of the eight weeks of the intervention. Method of measurement: by Realtime -PCR method.;GASP-1. Timepoint: 48 hours before the start of the intervention and after the end of the eight weeks of the intervention. Method of measurement: by Realtime -PCR method.	—

Measure

Time frame

GDF8. Timepoint: 48 hours before the start of the intervention and after the end of the eight weeks of the intervention. Method of measurement: by Realtime -PCR method.;GDF11. Timepoint: 48 hours before the start of the intervention and after the end of the eight weeks of the intervention. Method of measurement: by Realtime -PCR method.;Activin Reseptor IIß. Timepoint: 48 hours before the start of the intervention and after the end of the eight weeks of the intervention. Method of measurement: by Realtime -PCR method.;GASP-1. Timepoint: 48 hours before the start of the intervention and after the end of the eight weeks of the intervention. Method of measurement: by Realtime -PCR method.

—

Secondary

Measure	Time frame
Water Resistance training. Timepoint: before the start of the intervention and after the completion of eight weeks of the intervention. Method of measurement: It is measured by the level of perception of the RPE effort.	—

Countries

Iran (Islamic Republic of)

Contacts

Public Contactmaryam mousavi

Islamic Azad University

mousavi.maryam745@gmail.com+98 21 4486 8495

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026