Postoperative pain after mandibular wisdom tooth surgery.
Conditions
Interventions
Intervention group: In the intervention group, the patient will be given an oral capsule pregabalin (a structural analogue of gamma-aminobutyric acid) 75 mg (Actoverco company) along with 50 mL of wat
Sponsors
Gorgan University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 51 Years
Inclusion criteria
Inclusion criteria: Individuals aged between 18 to 50 years with impacted mandibular third molars and similar degrees of mesioangular impaction.
Exclusion criteria
Exclusion criteria: Systemic diseases (e.g., osteoporosis, hyperparathyroidism, chronic kidney disease, connective tissue autoimmune diseases, diabetes, thyroid disorders, etc.). Use of medications that may interact with pregabalin (e.g., sedatives, muscle relaxants, anxiolytics, antidepressants, anticonvulsants, oral diabetes medications, and angiotensin inhibitors). History of alcohol addiction. Allergy to pregabalin or related drugs Pregnancy and lactation. Use of analgesic or anti-inflammatory drugs within 24 hours prior to surgery. Clinical or radiographic evidence of active oral inflammation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pain score on the Visual Analog Scale (VAS). Timepoint: 2, 4, 6, and 8 hours after the surgery. Method of measurement: Visual Analog Scale (VAS). | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactHaleh zokaee
Gorgan University of Medical Sciences
Outcome results
None listed