renal stone. Calculus of kidney
Conditions
Interventions
Intervention 1: Intervention group1: receiving 5 mg of tadalafil and 0.4 mg of tamsulosin daily for two weeks. Intervention 2: 0.4 mg tamsulosin placebo tadalafil nightly.
Sponsors
Kerman University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Patients older than 18 years Having stones with a size between 5 and 20 mm in the kidney and proximal ureter
Exclusion criteria
Exclusion criteria: Having coagulation disorders pregnancy Creatinine clearance below 50 ml/min Liver dysfunction Urgent surgery is needed to remove stone blockage Presence of positive urine culture Patients with simultaneous unilateral or bilateral ureteral stones The distance between the stone and the skin is more than 12 cm History of previous unsuccessful extracorporeal lithotripsy Use of nitroglycerin and netirocanthine Lack of consent to participate in the study Systolic blood pressure below 90 mm Hg at the time of treatment initiation History of cataract History of hypersensitivity after taking tamsulosin or tadalafil History of back ache History of Severe digestive disorders after treatment History of priapism
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Stone-free status. Timepoint: two weeks later. Method of measurement: CT Scan. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMohammadamin Hesamarefi
Kerman University of Medical Sciences
Outcome results
None listed