breast cancer skin lesion. Secondary malignant neoplasm of skin
Conditions
Interventions
Intervention 1: Intervention group: Propofol injection before electrochemotherapy, with a dose of 25 -75 macro/min/kg in breast cancer patients with skin metastasis who are candidates for electrochemo
Sponsors
Shahid Beheshti University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: Symptomatic metastatic skin lesions (like bleeding, exudation, smell or ulceration) development of skin metastases, in which the symptoms mentioned can be expected Patients who receive systemic treatment and have a good effect on their primary cancer, but their skin lesions do not respond to these treatments or are progressing patients preferring electrochemistry multiple skin lesions or a lesion larger than 1 cm ASA group II, I, III patients between 18 and 60 years old
Exclusion criteria
Exclusion criteria: Pregnancy and breastfeeding Allergy to any of the drugs used in the study hypertension impaired liver and kidney function Hereditary heart diseases ischemic heart disease, smoking using beta blockers and sedative drugs refusing to sign an informed consent form
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Assessment of patient recovery time with Aldrete score based on assessment of vital signs and consciousness. Timepoint: after operation. Method of measurement: Aldrete score.;Neuropathic pain scale. Timepoint: before and after operation. Method of measurement: neuropathic pain scale.;Ramsay sedation scale. Timepoint: before, during and after operation. Method of measurement: Ramsay sedation scale.;Bispectral index. Timepoint: during operation. Method of measurement: Bispectral index sensor. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactSogol Asgari
Shahid Beheshti University of Medical Sciences
Outcome results
None listed