Comparison of the effect of letrozole plus N-acetylcysteine and letrozole plus dexamethasone on pregnancy rates in patients with polycystic ovary disease

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20240514061800N8

Enrollment

277

Registered

2025-08-26

Start date

2025-11-22

Completion date

Unknown

Last updated

2025-09-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Polycystic Ovary Disease. Supervision of high risk pregnancy, unspecified

Interventions

Intervention 1: Intervention group: They receive 5 mg of letrozole, with 1200 mg of N-acetylcysteine ??for 5 days. Intervention 2: Control group: They receive 5 mg of letrozole daily along with half a

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: Infertility The presence of at least one diseased tube

Exclusion criteria

Exclusion criteria: Thyroid dysfunction Oligozoospermia Ovarian cyst size greater than 6 cm

Design outcomes

Primary

Measure	Time frame
Endometrial Thickness. Timepoint: 5 days after the start of the intervention. Method of measurement: Ultrasound.;The Patient's Fertility Rate. Timepoint: 5 days after the start of the intervention. Method of measurement: Laboratory Method.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactFarahnaz Farzane

Iran University of Medical Sciences

f.farzaneh2019@gmail.com+98 21 5560 6034

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026