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Comparison of the effect of the combination of letrozole and clomiphene in stimulating ovulation in intrauterine insemination cycles with letrozole alone: ??A clinical trial study

Comparison of the effect of the combination of letrozole and clomiphene in stimulating ovulation in intrauterine insemination cycles with letrozole alone: ??A clinical trial study

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT20240514061800N10
Enrollment
160
Registered
2026-02-24
Start date
2026-04-21
Completion date
Unknown
Last updated
2026-06-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Intrauterine insemination. Normal Pregnancy

Interventions

Intervention 1: Intervention group: In this group, letrozole is given at a dose of 2.5-5 milligrams (made by the same company) daily from the third to the seventh day of the cycle. Intervention 2: Int

Sponsors

Shahid Beheshti University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female

Inclusion criteria

Inclusion criteria: Women 40 years old or younger Infertile couples with intermediate male factor Couples with unexplained infertility

Exclusion criteria

Exclusion criteria: Women over 40 years old The presence of abnormal hormone tests Severely abnormal spermogram The presence of an abnormal HSG, either in terms of the uterine cavity or in terms of blockage of the fallopian tubes

Design outcomes

Primary

MeasureTime frame
Measuring ßHCG levels. Timepoint: Two weeks after the intervention. Method of measurement: Using the laboratory method.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactTayebe Esfidani

Shahid Beheshti University of Medical Sciences

Esfidani.tayebeh@gmail.com+98 21 23871

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Jun 11, 2026