infertility. Female infertility associated with female factors
Conditions
Interventions
Intervention 1: Intervention group: On the trigger day with GnRH agonist, they will receive cabergoline 0.5 mg orally once daily for 7 days. Intervention 2: Control group: They will receive cabergolin
Sponsors
Tehran University of Medical Sciences
Eligibility
Sex/Gender
Female
Age
18 Years to 40 Years
Inclusion criteria
Inclusion criteria: Patients in the age range of 15 to 40, having at least one year of infertility history, patients with polycystic ovary syndrome using the Rotterdam criteria approved by the Rotterdam Joint Group in 2004. These criteria include having 17 or more follicles with a diameter of 10 mm or more on the trigger day, a peak estradiol level above 3,500 pg/ml, use of a GnRH antagonist protocol, use of a GnRH agonist, and cycles in which all embryos were cryopreserved. .
Exclusion criteria
Exclusion criteria: Having a history of sensitivity to cabergoline and other dopamine agonists, having heart, kidney, and liver disease, low response to ovarian stimulation and thus not being at risk of developing ovarian hyperstimulation syndrome, history of hyperprolactinemia.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Reducing the rate of ovarian hyperstimulation syndrome. Timepoint: After the intervention. Method of measurement: Transvaginal ultrasound and estradiol level measurement. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public Contactshahedeh khansari
Tehran University of Medical Sciences
Outcome results
None listed