Effect of probiotics on blood lipid level

Evaluation of the Effect of combination Lactobacillus casei, Lacticaseibacillus rhamnosus, and Lactobacillus acidophilus Probiotics on Blood Cholesterol Levels in Patients with Mild Hypercholesterolemia Compared to a Control Group.

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20240512061765N1

Enrollment

Registered

2024-07-14

Start date

2024-07-22

Completion date

Unknown

Last updated

2024-07-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Condition 1: MILD HYPERCHOLESTEROLEMIA ( total cholesterol 220-280 mg/dl). Condition 2: blood glucose level as beside finding. Pure hypercholesterolemia Other abnormal glucose

Interventions

Intervention 1: Intervention group: daily use of one capsule of BIO IBS from TAKGENE PHARMA company that contains 5*109 UFC( 5 billion) of of lactobacillus casei , Lacticaseibacillus rhamnosus , La

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: • Adults aged 18-65 years • Individuals with mild hypercholesterolemia(total cholesterol: 5.2-7.5 mmol/L)

Exclusion criteria

Exclusion criteria: Pregnant or lactating women Individuals on antibiotics or probiotics within the past three months. Individuals with severe health conditions affecting cholesterol metabolism

Design outcomes

Primary

Measure	Time frame
Total cholesterol. Timepoint: before trial and six weeks of medication use. Method of measurement: blood sampling.	—

Secondary

Measure	Time frame
Blood glucose level. Timepoint: before trial and after 6 weeks of medication use. Method of measurement: blood sampling.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactFatemeh Malekpour

Shiraz University of Medical Sciences

malekpour.f.81@gmail.com+98 71 3647 4967

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026