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The Effect of Citrus Medicine Paste on Nausea Caused by Chemotherapy in Breast Cancer

Investigating the Effect of Citrus Medicine Paste on Acute Nausea and Vomiting Caused by Chemotherapy in Breast Cancer Patients

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
IRCT
Registry ID
IRCT20240511061734N1
Enrollment
140
Registered
2024-05-23
Start date
2024-05-21
Completion date
Unknown
Last updated
2024-05-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Condition 1: Nausea and vomiting. Condition 2: female breast cancer. Condition 3: breast cancer. Condition 4: citrus medica. Nausea and vomiting Malignant neoplasm of central portion of breast Intraductal carcinoma in situ of breast

Interventions

Intervention 1: Intervention group: People Suffering from Nausea and Vomiting Caused by Breast Cancer Chemotherapy, Who Receive One Tablespoon (10 Grams) Of Citrus Medica Paste Half an Hour Before Bre

Sponsors

Tehran University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Women Aged 18 Years And Older Who Have Breast Cancer Definitive Diagnosis Of Breast Cancer With The Opinion Of Hemato-Oncologist And Pathologist History Of Receiving At Least One Course Of Chemotherapy Due To Breast Cancer History Of Experiencing Nausea Or Vomiting Following Chemotherapy Sessions Not Receiving Anti-Nausea And Vomiting Medicine In The Last 24 Hours Not Having A History Of Nausea And Vomiting Due To Reasons Other Than Chemotherapy (Such As High Blood Pressure, Kidney Failure, Liver And Digestive Problems Causing Nausea) Absence Of Hepatitis, Gastrointestinal Obstruction, Brain Malignancies Or Brain Metastases Absence Of Allergy To Citron

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
CINV score in INVR questionnaire. Timepoint: Each Patient Is Evaluated Six Times (One Hour Before Chemotherapy, 12 Hours After Chemotherapy and On the Second, Third, Fourth and Fifth Days After Chemotherapy). Method of measurement: INVR questionnaire.;CINV score in VAS questionnaire. Timepoint: Each Patient Is Evaluated Six Times (One Hour Before Chemotherapy, 12 Hours After Chemotherapy and On the Second, Third, Fourth and Fifth Days After Chemotherapy). Method of measurement: VAS questionnaire.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSeyed Peyman Khamechi

Tehran University of Medical Sciences

khamechi-p@razi.tums.ac.ir+98 21 8897 4535

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026