Systemic lupus erythematosus. Systemic lupus erythematosus (SLE)
Conditions
Interventions
Intervention 1: Intervention group: They received synbiotic capsules for 8 weeks. Intervention 2: Control group: received placebo for 8 weeks.
Sponsors
Ardabil University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Definitive diagnosis of SLE Age above 18 years
Exclusion criteria
Exclusion criteria: Taking antibiotics pregnancy breastfeeding Uncontrolled blood pressure Suffering from other autoimmune diseases diabetes Severe kidney and liver disease Life-threatening SLE including lupus nephritis and CNS involvement Lupus vasculitis peritonitis severe hemolysis Platelets less than 40,000 Endocarditis Alveolar hemorrhage Lupus pneumonia OCP intake Taking supplements containing antioxidants or omega-3 in the last month Sensitivity to synbiotics Smoking and alcohol consumption
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Total antioxidant capacity: measures the antioxidant capacity. Malondialdehyde: shows the level of oxidative stress. Timepoint: At the beginning of the study and then 8 weeks after taking drugs and placebo. Method of measurement: The level of (MDA) and (TAC) in serum samples is measured using a spectrophotometer with a colorimetric method. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public Contactyousef mohammadi kebar
Ardabil University of Medical Sciences
Outcome results
None listed